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Pet Parent Educational Resources

Keep your clients, clinic and neighborhood safe from leptospirosis with these resources.

These are designed to be shared at your clinic, through social media and more.

Zoonotic Risks
Video

Help pet parents understand the risks associated with leptospirosis and how to take precautions to protect their pets and family.

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Signs of Disease
Video

Help pet parents to recognize the signs and symptoms of leptospirosis.

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Leptospirosis Basics
Video

Use this informative overview to help your parents understand leptospirosis the disease, its significance and how to minimize risks for their dog.

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Diagnosis & Treatment
Video

Share this basic video to help pet parents understand treatment options for leptosiprosis as well as what they can do to reduce their dog's risk.

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Risks & Prevention
Video

Help pet parents keep their pets safe with these preventative measures.

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Understand your dog's risk
Pet Parent Guide

Share this printable brochure to educate pet parents in your clinic about transmission, risks and outcomes.

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Infographic Map
Handout

A simple reference for facts presented in a visual way–a great resource for sharing online.

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Dangers of Lepto
PetLife Radio Podcast

Hear leading veterinary experts Dr. Courtney Campbell and Dr. Michelle Evanson discuss leptospirosis and how to prevent this dangerous zoonotic disease.

Listen
Protect Your Pets & Family from Leptospirosis
Video

Renowned pet journalist and radio host Steve Dale discusses protecting your pets & family from leptospirosis.

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Rain & Leptospirosis
Blogs

Renowned pet journalist and radio host, Steve Dale discusses how rain may be linked to increase in leptospirosis.

Read

Professsional Leptospirosis Resources

Video, digital and print assets for professional use.

Share with clinic staff and other professionals to help prevent the spread of leptospirosis.

Standard Operating Procedure
Video

Learn why it's important to have a Standard Operating procedure to reduce the risk of leptospirosis in you practice.

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Standard Operating Procedure
Handout

A quick reference to remind staff of tips and rules for preventing further spread to other animals or humans.

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Standard Operating Procedure
Booklet

Review this detailed protocol with your staff to teach the “Recognize, React, Reduce” method of safely handling leptospirosis within the clinic.

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Quick Guide to Lepto
eBook

A handy guide to protect dogs and prevent the spread of leptospirosis by identifying risk factors and signs.

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Lepto Basics
Video

Watch this quick video highlighting the dangers of leptospirosis for pets and pet families.

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Signs & Symptoms
Video

Stay alert for these signs of leptospirosis to prevent the spread of this potentially deadly disease.

Watch
Treatment Options
Video

An informative list of treatment options available if a pet in your care has leptospirosis.

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Preventing Lepto
Video

Learn which dogs are most at risk, and how you can help prevent dogs from contracting leptospirosis.

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Zoonotic Risks
Video

Help prevent the spread of leptospirosis between dogs, other pets and humans with these tips.

Watch
Leptospirosis Basics
Podcast

Hear what makes the spread of leptospirosis unpredictable, and why you should be concerned.

Listen
Client Communication
Podcast

Learn how to approach the conversation about vaccination for leptospirosis with your pet parents.

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Vaccine Safety
Podcast

Fact vs Fiction - listen to the latest thoughts from veterinary experts on vaccinating for leptospirosis.

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Clinic Safety
Podcast

Listen to the latest in infection control including safe handling of lepto patients and protection for clinic staff.

Listen
Lepto Reporting
Podcast

Why incidence reporting is important and current reporting methods.

Listen
AAHA Vaccine Guidelines
Lifestyle Calculator

Determine vaccination recommendations based on a dog's lifestyle, age, and other risk factors.

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AAHA Vaccination Guidelines

Find out the latest from AAHA on lifestyle vaccines as well as safe vaccine handling and other FAQs in the updated AAHA Canine Vaccination Guidelines.

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Lepto SOP CE Course
Webinar

Why awareness & diagnosis is crucial to the health of your patients, clients, & practice.

Learn More
book_icon Read
Disease & Mortality Study
Read the study which proves high efficacy of Nobivac® Lepto4 vaccine under severe challenge.
PREVENTION OF DISEASE AND MORTALITY IN VACCINATED DOGS FOLLOWING EXPERIMENTAL CHALLENGE WITH VIRULENT LEPTOSPIRA.

R LaFleur, J Dant, T Wasmoen. Intervet / Schering Plough Animal Health, Elkhorn, NE.

Canine Leptospirosis can vary from subclinical infection to illness that ranges from mild to severe, including death, depending on the susceptibility of the dog, virulence of the organism, and route and degree of infection. The objective of this study was to evaluate the ability of a canine Leptospira bacterin to prevent infection and disease following challenge with virulent Leptospira canicola, L. pomona, L. grippotyphosa, or L. icterohaemorrhagiae. Groups of 8-week-old beagles were vaccinated (day 0) and boosted (day 21) with placebo (n = 10) or the 4-way bacterin (n ≥ 20) and subsequently challenged with each serovar. The results demonstrated that blood and various tissue samples from placebo-recipients became reliably infected, and the dogs developed typical clinical signs of Leptospirosis including loss of appetite, ocular congestion, depression, dehydration, jaundice, hematuria, melena, vomiting, petechiae, and death. In addition, placebo-recipients developed kidney and liver dysfunction. In contrast, some vaccine-recipients became infected, but the organisms were cleared quickly from the blood. Vaccinated dogs failed to develop severe clinical disease requiring medical intervention, and no animals died (p ≥ 0.001). A few of the vaccinated dogs developed clinical abnormalities, but the clinical signs remained mild and were self-limiting (p < 0.0001 for each serovar). Administration of the bacterin also prevented thrombocytopenia (p < 0.0001), kidney complications caused by L. canicola (p < 0.0001), L. icterohaemorrhagiae (p < 0.0001), and L. pomona (p = 0.012), and liver dysfunction caused by L. pomona (p < 0.0001) and L. grippotyphosa (p < 0.0001). The results therefore confirmed that vaccinating dogs with the 4-way Leptospira bacterin provided a high degree of protection (99.5%-100%) against the clinical signs of Leptospirosis including mortality.

book_icon Read
Urinary Shedding Challenge Study
Read the study which proves Nobivac® Canine 1-DAPPv+L4 effectively protects against leptospiremia and leptospiruria of (4) serovars.
PREVENTION OF LEPTOSPIREMIA AND LEPTOSPIRURIA FOLLOWING VACCINATION WITH A DAPPV + 4-WAY LEPTOSPIRA COMBINATION VACCINE

Rhonda L. LaFleur, Jennifer C. Dant, Anna L. Tubbs, Huchappa Jayappa, David Sutton, Ian Tarpey

Background: Leptospirosis, characterized by high fever, anorexia, vomiting, abdominal pain, diarrhea, myalgia, polyuria/polydipsia, jaundice, epistaxis, hematuria, and/or reproductive failure, continues to cause considerable morbidity among infected canines. Direct transmission of Leptospira spp. occurs when dogs come into contact with infected urine or ingest infected tissue. After dogs become infected, the spirochetes circulate in the blood for several days,1,3 where they cause extensive damage to the endothelium of small blood vessels (leptospiremia). After the leptospiremic phase, the spirochetes can further colonize various organs, including the kidneys, where dogs can become a carrier and potentially shed organisms in the urine for months (leptospiruria). Leptospira interrogans serovars Canicola and Icterohaemorrhagiae are traditional causative agents of canine leptospirosis, and while the use of bacterins have decreased the prevalence of the disease, significant morbidity can still be attributed to infection with these serovars.

Aim of the Work: In this study, we combined inactivated L interrogans serovars Canicola, Pomona, and Icterohaemorrhagiae and L kirschneri serovar Grippotyphosa with Nobivac® Canine 1-DAPPv (Animal Health at Merck & Co., Inc., Kenilworth, NJ USA), a commercially available vaccine that contains modified live canine distemper virus, adenovirus, parainfluenza virus, and parvovirus. We then vaccinated dogs with the combination product and evaluated the ability of the vaccination to prevent leptospiremia and leptospiruria following challenge with viable organisms of each serovar.

Read More about this study here