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Transmission of Leptospirosis

rat photo

Infected animal urinates in water or on wet ground.

dog photo

Dog plays, swims or drinks from contaminated water.

dog photo

Dog contracts leptospirosis through contact with urine of infected animal and becomes a carrier.

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Reported cases of zoonotic diseases are on the rise, and are expected to continue to increase2,3

  • Prevalence of canine leptospirosis has increased in recent years2,3
  • As many as 8.2% of dogs are shedding leptospires, some asymptomatically4
  • Weather changes, population growth, and habitat encroachment have all increased human and canine exposure to pathogens and their carriers2,3

Leptospirosis Risks

Leptospirosis Presents Multiple Threats to Your Patients

Dogs at Risk

Dogs at Risk

Dogs at greatest risk for developing leptospirosis include those with:5

  • Access to ponds, lakes, streams, standing water, or puddles
  • Exposure to urine from other infected animals or through contaminated water
Dog at Risk

Spreading Disease

As leptospirosis progresses, it can result in Leptospiruria (urinary shedding)5

Morbidity Threats

As leptospirosis progresses, it can result in:5

  • Vascular damage
  • Thrombocytopenia
  • Severe kidney and liver damage
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Unmatched Protection of Nobivac® Lepto4

The first and only 4-way canine leptospirosis vaccine specifically indicated to protect against disease, mortality and leptospiruria (urinary shedding).

Nobivac Product

2 Critical Indications

1. SHEDDING: defense against urinary shedding caused by 4 key Leptospira serovars
Nobivac® Lepto prevents leptospiruria associated with
  • L. grippotyphosa
  • L. canicola
  • L. icterohaemorrhagiae
Nobivac Lepto aids in the prevention of leptospiruria associated with
  • L. pomona
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2. MORTALITY: the only leptospirosis vaccine indicated to aid in the prevention of disease and mortality
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Protection for Dogs Facing the Most Severe Challenges

Clinical efficacy results showed that Nobivac® Canine 1-DAPPv+L4 also prevented1
  • Leptospiremia
  • Liver dysfunction
  • Thrombocytopenia
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Nobivac® Lepto4 Offers Unmatched Protection6-9

Nobivac® Lepto4 is the clear choice when compared with other 4-way leptospirosis vaccines. Nobivac Table Learn More About Nobivac® Lepto4

Vaccipure Filtration Technology

A Strategic Advance:
VacciPure Filtration Technology1

Merck Animal Health has introduced the special VacciPure filtration process in manufacturing Nobivac Nobivac® Lepto4 and Nobivac® Canine 1-DAPPv+L4 to promote an even higher level of vaccine quality.

A porous filtration membrane selectively removes extraneous proteins, salts, and solvents

  • The outcome – fewer total proteins and a more purified final product